ea0037gp.15.01 | Diabetes and obesity – basic | ECE2015
Patil Swapnil
, Chen Xizhe
, Watson Luke
, Loftus Paul
, Flynn Lisa O'
, Chandler Lois
, Rubanyi Gabor
, Elliman Stephen
, O'Brien Timothy
Non-healing foot ulcers are a major complication in diabetic patients. Mesenchymal stem cells (MSCs) are known to promote angiogenesis with improved wound healing. Orbsen Therapeutics has identified a novel antibody (CD362+) which can be used to prospectively FACS-isolate CD362+CD45− MSC from human bone marrow with enhanced MSC/MNC purity ratios of up to 1/4. Excellagen matrix was used to seed the cells as biomaterials are well reported t...